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How to distinguish between different forms of human Interleukin 4
Distinguish_btwn_IL-4/IL-4_4D9_stored.JPG
Figure 1. Clone 3H4 appears to recognize IL-4 in activated cells. Positive staining (red) is seen as ring pattern on cells in the submucosa and epithelium of nasal polyp (panel A) and cells scattered through the tonsil (panel B). Clone 4D9 stains stored human interleukin 4 as seen in the cytoplasm of cells in nasal polyp (panel C) and tonsil (panel D) sections. (40 x magnification).
Images are courtesy of Dr. Susan Wilson of the Southampton General Hospital, Department of Medicine.
References:
1. Bradding, P. et al. J.Exp. Med. 176:1381-1386 (1992)
2. Bradding, P. et al. Am. J. Respir. Cell Mol. Biol. 10:471-480 (1994)
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